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IRAK4 adenovirus


Product Name: Ad-IRAK4

Product Category: Ready-use human Adenovirus Type5 (dE1/E3)

Gene Name: IRAK4

Gene Alias: IRAK4, REN64, NY-REN-64, IRAK-4

GeneBank Number: BC013316

Description:

Interleukin-1 receptor (IL1R)-associated kinases (IRAKs) are important mediators in the signal transduction of Toll-like receptor (TLR) and IL-1R family members, collectively referred to as TIRs. Binding of IL-1 to its cognate receptor results in the activation of the NFkB signaling pathway. 100 kDa IRAK-1 is implicated as an upstream mediator of NFkB activation. IRAK-2 is a proximal mediator of IL-1, a component of the IL-1R signaling complex and is required for IL-1R-induced NFkB activation. IRAK-4 is strongly expressed in kidney and is also found in lung, testis, small intestine, breast, liver, and placenta. In contrast to the other IRAKs that are expressed in most cell types, IRAK-M is restricted to monocytic cells.

Titer: 1x1010 PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

Catalog No. Tag Promoter Species Price **
1578 CMV human $690.00

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