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Dual specificity phosphatase 4 adenovirus


Product Name: Ad-MKP2

Product Category: Ready-use human Adenovirus Type5 (dE1/E3)

Gene Name: MKP2

Gene Alias: TYP, HVH2, MKP2, DUSP4, MKP-2

GeneBank Number: BC014565

Description:

Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4.

Titer: 1x1010 PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

References:

  • Glutathione Peroxidase-1 (GPx-1) deficiency augments pro-inflammatory cytokine-induced redox signaling and human endothelial cell activation
    JBC. 2011. :Epub

Catalog No. Tag Promoter Species Price **
1574 CMV human $475.00

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