v-raf murine sarcoma 3611 viral oncogene homolog Gene adenovirus
Product Name: Ad-A-Raf
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Gene Name: A-Raf
Gene Alias: ARAF, PKS2, A-RAF, ARAF1, RAFA1
GeneBank Number: BC002466
Description: The Raf kinases are important intermediates in signal transduction pathways. Raf-1, the prototype member of this gene family, is a 72-76 kDa cytoplasmic protein with intrinsic serine/threonine kinase activity, is broadly expressed in many cell types and is the cellular homolog of the viral oncogene, v-Raf. Other members of the Raf gene family include Raf-A and Raf-B. Raf-1 phosphorylates and thereby activates MEK (also designated MAP kinase kinase). Ras proteins bind Raf-1, but only when Ras is in its active GTP-binding state. This interaction results in Raf-mediated MEK activation. Two more recently described Raf-related proteins, Ksr-1 and Tak1 (TGF-beta-activated kinase), function as upstream regulators of Ras signaling pathways.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1510 |
|
CMV |
|
human |
$690.00 |
|
