human SBDS shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SBDS

Gene Name

SBDS ribosome assembly guanine nucleotide exchange factor

Gene ID

51119

Gene Synonyms

CGI-97; SDS; SWDS

ORF Size

753 bp

RefSeq#

NM_016038

Gene Description

SBDS encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. SBDS has a closely linked pseudogene that is distally located.

UniGene ID

Hs.110445

HGNC ID

HGNC:19440