mouse SBDS shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Sbds.
shADV-271382
Ad-m-SBDS-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sbds (Shwachman-Bodian-Diamond syndrome homolog (human)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4733401P19Rik; AI836084; CGI-97; SDS
Description (Vector)
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
Gene ID
66711
Gene Name (Vector)
Shwachman-Bodian-Diamond syndrome homolog (human)
Gene Symbol
Sbds
ORF Size (aa)
753
RefSeq ID
NM_023248
RefSeq Synonyms
NM_023248, BC003849,
Species
mouse
UniGene ID
Mm.280484
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.