human KCNH2 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

KCNH2

Gene Name

potassium voltage-gated channel, subfamily H (eag-related), member 2

Gene ID

3757

Gene Synonyms

ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1

ORF Size

2460 bp

RefSeq#

NM_000238

Gene Description

KCNH2 encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.

UniGene ID

Hs.647099

HGNC ID

HGNC:6251