human KCNH2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KCNH2.
shAAV-212697
AAV-h-KCNH2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KCNH2 (potassium voltage-gated channel, subfamily H (eag-related), member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1
Description (Vector)
KCNH2 encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.
Gene ID
3757
Gene Name (Vector)
potassium voltage-gated channel, subfamily H (eag-related), member 2
Gene Symbol
KCNH2
HGNC ID
HGNC:6251
ORF Size (aa)
2460
ORF Size (bp)
2460 bp
RefSeq ID
NM_000238
RefSeq Synonyms
NM_172057, NM_172056, NM_001204798, NM_000238, BC167862,
Species
human
UniGene ID
Hs.647099
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.