mouse WEE2 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-281204
Availability:
6-8 weeks
Name:
AAV-m-WEE2-shRNA
This is an AAV expressing shRNA for silencing of Mouse Wee2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Wee2
- Gene Name
- WEE1 homolog 2 (S. pombe)
- Gene ID
- 381759
- Gene Synonyms
- Gm1065; Wee1B
- ORF Size
- 1668 bp
- RefSeq#
- NM_201370
- Gene Description
- Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
- UniGene ID
- Mm.20593
Related Products
Product | Cat No. |
---|---|
AAV-h-WEE2 | AAV-227756 |
AAV-m-WEE2 | AAV-281204 |
Ad-h-WEE2 | ADV-227756 |
Ad-m-WEE2 | ADV-281204 |
AAV-h-WEE2-shRNA | shAAV-227756 |
Ad-h-WEE2-shRNA | shADV-227756 |
Ad-m-WEE2-shRNA | shADV-281204 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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