mouse WEE2 Adenovirus

Name
Ad-m-WEE2

Cat No
ADV-281204

Availability
4-5 weeks

This is an Adenovirus expressing Mouse Wee2.

ADV-281204

Ad-m-WEE2

Ready-to-use Adenovirus expressing Mouse Wee2 (WEE1 homolog 2 (S. pombe)). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Gm1065; Wee1B

Description (Vector)

Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

Gene ID

381759

Gene Name (Vector)

WEE1 homolog 2 (S. pombe)

Gene Symbol

Wee2

ORF Size (aa)

1668

ORF Size (bp)

1668 bp

RefSeq ID

NM_201370

RefSeq Synonyms

NM_201370, BC080784, BC052883,

Species

mouse

UniGene ID

Mm.20593

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.