mouse TFRC shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-274094
Availability:
Immediate
Name:
AAV-m-TFRC-shRNA
This is an AAV expressing shRNA for silencing of Mouse Tfrc.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Tfrc
- Gene Name
- transferrin receptor
- Gene ID
- 22042
- Gene Synonyms
- 2610028K12Rik; CD71; E430033M20Rik; Mtvr1; p90; TFR; TFR1; TR; Trfr
- ORF Size
- 2292 bp
- RefSeq#
- NM_011638
- Gene Description
- Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
- UniGene ID
- Mm.28683
Related Products
Product | Cat No. |
---|---|
AAV-h-TFRC | AAV-225374 |
AAV-m-TFRC | AAV-274094 |
Ad-h-TFRC | ADV-225374 |
Ad-m-TFRC | ADV-274094 |
AAV-h-TFRC-shRNA | shAAV-225374 |
Ad-h-TFRC-shRNA | shADV-225374 |
Ad-m-TFRC-shRNA | shADV-274094 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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