mouse SYNM shRNA silencing AAV

Cat. No: shAAV-273539

Availability: 6-8 weeks

Name: AAV-m-SYNM-shRNA

This is an AAV expressing shRNA for silencing of Mouse Synm.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Synm
Gene Name: synemin, intermediate filament protein
Gene ID: 233335
Gene Synonyms: 4930412K21Rik; AI852401; Dmn; E130104F11; Syn; Synemin
ORF Size: 4686 bp
RefSeq#: NM_207663
Gene Description: Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
UniGene ID: Mm.60526