mouse RSPO4 shRNA silencing AAV

Cat. No: shAAV-271191

Availability: 6-8 weeks

Name: AAV-m-RSPO4-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rspo4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rspo4
Gene Name: R-spondin 4
Gene ID: 228770
Gene Synonyms: A730099F22; A930029K19Rik
ORF Size: 687 bp
RefSeq#: NM_001040689
Gene Description: Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway (By similarity).
UniGene ID: Mm.159868