human RSPO4 shRNA silencing Adenovirus

Name
Ad-h-RSPO4-shRNA

Cat No
shADV-222067

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human RSPO4.

shADV-222067

Ad-h-RSPO4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RSPO4 (R-spondin 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

C20orf182; CRISTIN4

Description (Vector)

RSPO4 encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.

Gene ID

343637

Gene Name (Vector)

R-spondin 4

Gene Symbol

RSPO4

HGNC ID

HGNC:16175

ORF Size (aa)

705

RefSeq ID

NM_001029871

RefSeq Synonyms

NM_001040007, NM_001029871, BC156852,

Species

human

UniGene ID

Hs.444980

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.