mouse HTRA3 shRNA silencing AAV

Cat. No: shAAV-261791

Availability: 6-8 weeks

Name: AAV-m-HTRA3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Htra3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Htra3
Gene Name: HtrA serine peptidase 3
Gene ID: 78558
Gene Synonyms: 2210021K23Rik; 9530081K03Rik; Prsp; Tasp
ORF Size: 1380 bp
RefSeq#: NM_030127
Gene Description: Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.
UniGene ID: Mm.274255