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mouse HTRA3 shRNA silencing Adenovirus

Name 
Ad-m-HTRA3-shRNA
Cat No 
shADV-261791
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Htra3.

shADV-261791
Ad-m-HTRA3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Htra3 (HtrA serine peptidase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2210021K23Rik; 9530081K03Rik; Prsp; Tasp
Description (Vector)
Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.
Gene ID
78558
Gene Name (Vector)
HtrA serine peptidase 3
Gene Symbol
Htra3
ORF Size (aa)
1380
ORF Size (bp)
1380 bp
RefSeq ID
NM_030127
RefSeq Synonyms
NM_030127, NM_001042615, BC138588, BC138587,
Species
mouse
UniGene ID
Mm.274255

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.