mouse ELMO3 shRNA silencing AAV

Cat. No: shAAV-258295

Availability: 6-8 weeks

Name: AAV-m-ELMO3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Elmo3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Elmo3
Gene Name: engulfment and cell motility 3
Gene ID: 234683
Gene Synonyms: 9930107J06; BC058752; CED-12; Ced12
ORF Size: 1773 bp
RefSeq#: NM_172760
Gene Description: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).
UniGene ID: Mm.237966