human HIST2H4A shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-231822
Availability:
6-8 weeks
Name:
AAV-h-HIST2H4A-shRNA
This is an AAV expressing shRNA for silencing of Human HIST2H4A.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HIST2H4A
- Gene Name
- histone cluster 2 H4 family member a
- Gene ID
- 8370
- Gene Synonyms
- FO108; H4; H4/n; H4F2; H4FN; HIST2H4
- ORF Size
- 309 bp
- RefSeq#
- NM_003548
- Gene Description
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
- UniGene ID
- Hs.655235
- HGNC ID
- HGNC:4794
Related Products
Product | Cat No. |
---|---|
AAV-h-HIST2H4A | AAV-231822 |
AAV-h-HIST2H4A | AAV-231849 |
Ad-h-HIST2H4A | ADV-231822 |
Ad-h-HIST2H4A | ADV-231849 |
Ad-h-HIST2H4A-shRNA | shADV-231822 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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