human RSPO4 shRNA silencing AAV

Cat. No: shAAV-222067

Availability: 6-8 weeks

Name: AAV-h-RSPO4-shRNA

This is an AAV expressing shRNA for silencing of Human RSPO4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RSPO4
Gene Name: R-spondin 4
Gene ID: 343637
Gene Synonyms: C20orf182; CRISTIN4
ORF Size: 705 bp
RefSeq#: NM_001029871
Gene Description: RSPO4 encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.444980
HGNC ID: HGNC:16175