human PRSS1 shRNA silencing AAV

Name
AAV-h-PRSS1-shRNA

Cat No
shAAV-220014

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PRSS1.

shAAV-220014

AAV-h-PRSS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRSS1 (protease, serine 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

TRP1; TRY1; TRY4; TRYP1

Description (Vector)

PRSS1 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. PRSS1 and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

Gene ID

5644

Gene Name (Vector)

protease, serine 1

Gene Symbol

PRSS1

HGNC ID

HGNC:9475

ORF Size (aa)

744

RefSeq ID

NM_002769

RefSeq Synonyms

NM_002769, BC128226, BC103998,

Species

human

UniGene ID

Hs.654498

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.