human SYCP3 shRNA silencing AAV

Name 
AAV-h-SYCP3-shRNA
Cat No 
shAAV-224798
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SYCP3.

shAAV-224798
AAV-h-SYCP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SYCP3 (synaptonemal complex protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COR1; RPRGL4; SCP3; SPGF4
Description (Vector)
SYCP3 encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
Gene ID
50511
Gene Name (Vector)
synaptonemal complex protein 3
Gene Symbol
SYCP3
HGNC ID
HGNC:18130
ORF Size (aa)
711
RefSeq ID
NM_153694
RefSeq Synonyms
NM_153694, NM_001177949, NM_001177948, BC062662,
Species
human
UniGene ID
Hs.506504

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.