human PDE6C shRNA silencing AAV

Cat. No: shAAV-218484

Availability: 6-8 weeks

Name: AAV-h-PDE6C-shRNA

This is an AAV expressing shRNA for silencing of Human PDE6C.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDE6C
Gene Name: phosphodiesterase 6C
Gene ID: 5146
Gene Synonyms: ACHM5; COD4; PDEA2
ORF Size: 2574 bp
RefSeq#: NM_006204
Gene Description: PDE6C encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. Mutations in this gene are associated with cone dystrophy type 4 (COD4).
UniGene ID: Hs.658121
HGNC ID: HGNC:8787