human GPR44 shRNA silencing AAV

Cat. No: shAAV-210356

Availability: 6-8 weeks

Name: AAV-h-GPR44-shRNA

This is an AAV expressing shRNA for silencing of Human PTGDR2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PTGDR2
Gene Name: prostaglandin D2 receptor 2
Gene ID: 11251
Gene Synonyms: CD294; CRTH2; DL1R; DP2; GPR44
ORF Size: 1188 bp
RefSeq#: NM_004778
Gene Description: PTGDR2 encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
UniGene ID: Hs.299567
HGNC ID: HGNC:4502