mouse GPR44 Over-expression AAV

Name 
AAV-m-GPR44
Cat No 
AAV-260642
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ptgdr2.

AAV-260642
AAV-m-GPR44

Ready-to-use AAV expressing Mouse Ptgdr2 (prostaglandin D2 receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Crth2; Gpr44; Grp45
Description (Vector)
Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
Gene ID
14764
Gene Name (Vector)
prostaglandin D2 receptor 2
Gene Symbol
Ptgdr2
ORF Size (aa)
1149
ORF Size (bp)
1149 bp
RefSeq ID
NM_009962
RefSeq Synonyms
NM_009962, BC111906,
Species
mouse
UniGene ID
Mm.470721

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.