human CLCN2 shRNA silencing AAV

Cat. No: shAAV-205349

Availability: 6-8 weeks

Name: AAV-h-CLCN2-shRNA

This is an AAV expressing shRNA for silencing of Human CLCN2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CLCN2
Gene Name: chloride voltage-gated channel 2
Gene ID: 1181
Gene Synonyms: CIC-2; clC-2; CLC2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; LKPAT
ORF Size: 2646 bp
RefSeq#: NM_004366
Gene Description: CLCN2 encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.436847
HGNC ID: HGNC:2020