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human CLCN2 Over-expression AAV

Name 
AAV-h-CLCN2
Cat No 
AAV-205349
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CLCN2.

AAV-205349
AAV-h-CLCN2

Ready-to-use AAV expressing Human CLCN2 (chloride voltage-gated channel 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CIC-2; clC-2; CLC2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; LKPAT
Description (Vector)
CLCN2 encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
Gene ID
1181
Gene Name (Vector)
chloride voltage-gated channel 2
Gene Symbol
CLCN2
HGNC ID
HGNC:2020
ORF Size (aa)
2646
ORF Size (bp)
2646 bp
RefSeq ID
NM_004366
RefSeq Synonyms
NM_004366, NM_001171089, NM_001171088, NM_001171087, BC072004, BC021578,
Species
human
UniGene ID
Hs.436847

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.