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human CLCN2 shRNA silencing AAV

Name 
AAV-h-CLCN2-shRNA
Cat No 
shAAV-205349
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CLCN2.

shAAV-205349
AAV-h-CLCN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLCN2 (chloride voltage-gated channel 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CIC-2; clC-2; CLC2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; LKPAT
Description (Vector)
CLCN2 encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
Gene ID
1181
Gene Name (Vector)
chloride voltage-gated channel 2
Gene Symbol
CLCN2
HGNC ID
HGNC:2020
ORF Size (aa)
2646
ORF Size (bp)
2646 bp
RefSeq ID
NM_004366
RefSeq Synonyms
NM_004366, NM_001171089, NM_001171088, NM_001171087, BC072004, BC021578,
Species
human
UniGene ID
Hs.436847

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.