rat SFRS10 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-292121
Availability:
3-5 weeks
Name:
AAV-r-SFRS10
This is an AAV expressing Rat Tra2b.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Rat
- Gene Symbol
- Tra2b
- Gene Name
- transformer 2 beta homolog (Drosophila)
- Gene ID
- 117259
- Gene Synonyms
- Sfrs10; Srsf10
- ORF Size
- 867 bp
- RefSeq#
- BC070948
- Gene Description
- Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.
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