mouse TRA2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tra2b.
shAAV-274882
AAV-m-TRA2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tra2b (transformer 2 beta homolog (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5730405G21Rik; D16Ertd266e; Sfrs10; SIG-41; Silg41; TRA2beta
Description (Vector)
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.
Gene ID
20462
Gene Name (Vector)
transformer 2 beta homolog (Drosophila)
Gene Symbol
Tra2b
ORF Size (aa)
690
RefSeq ID
NM_009186
RefSeq Synonyms
NM_009186, NM_001330555, NM_001330554, BC086795, BC061177,
Species
mouse
UniGene ID
Mm.442193
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.