mouse SEMA3E Over-expression AAV

Cat. No: AAV-271586

Availability: 3-5 weeks

Name: AAV-m-SEMA3E

This is an AAV expressing Mouse Sema3e.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Sema3e
Gene Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Gene ID: 20349
Gene Synonyms: 6430702L12; AA408817; mKIAA0331; Semah
ORF Size: 2328 bp
RefSeq#: BC057956
Gene Description: Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation (By similarity).
UniGene ID: Mm.134093