human MMP9 Over-expression AAV

Name 
AAV-h-MMP9
Cat No 
AAV-215606
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MMP9.

AAV-215606
AAV-h-MMP9

Ready-to-use AAV expressing Human MMP9 (matrix metallopeptidase 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLG4B; GELB; MANDP2; MMP-9
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Gene ID
4318
Gene Name (Vector)
matrix metallopeptidase 9
Gene Symbol
MMP9
HGNC ID
HGNC:7176
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
RefSeq ID
NM_004994
RefSeq Synonyms
NM_004994, BC006093,
Species
human
UniGene ID
Hs.297413

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.