human MMP9 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MMP9.
shADV-215606
Ad-h-MMP9-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MMP9 (matrix metallopeptidase 9). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLG4B; GELB; MANDP2; MMP-9
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Gene ID
4318
Gene Name (Vector)
matrix metallopeptidase 9
Gene Symbol
MMP9
HGNC ID
HGNC:7176
ORF Size (aa)
2124
ORF Size (bp)
2124 bp
RefSeq ID
NM_004994
RefSeq Synonyms
NM_004994, BC006093,
Species
human
UniGene ID
Hs.297413
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.