mouse CD86 Over-expression AAV

Cat. No: AAV-255056

Availability: 3-5 weeks

Name: AAV-m-CD86

This is an AAV expressing Mouse Cd86.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cd86
Gene Name: CD86 antigen
Gene ID: 12524
Gene Synonyms: B7; B7-2; B7.2; B70; Cd28l2; CLS1; ETC-1; Ly-58; Ly58; MB7; MB7-2; TS/A-2
ORF Size: 930 bp
RefSeq#: BC013807
Gene Description: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
UniGene ID: Mm.1452