mouse 2410022L05RIK Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-250740
Availability:
3-5 weeks
Name:
AAV-m-2410022L05RIK
This is an AAV expressing Mouse Coprs.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Coprs
- Gene Name
- coordinator of PRMT5, differentiation stimulator
- Gene ID
- 66423
- Gene Synonyms
- 1700029I03Rik; 2410022L05Rik; AA409325; AI256813; C85432; Copr5
- ORF Size
- 522 bp
- RefSeq#
- BC029192
- Gene Description
- Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression.
- UniGene ID
- Mm.29063
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