human ZAK Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-228028
Availability:
3-5 weeks
Name:
AAV-h-ZAK
This is an AAV expressing Human ZAK.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ZAK
- Gene Name
- sterile alpha motif and leucine zipper containing kinase AZK
- Gene ID
- 51776
- Gene Synonyms
- AZK; MLK7; mlklak; MLT; MLTK; MRK; pk; SFMMP
- ORF Size
- 1368 bp
- RefSeq#
- BC001401
- Gene Description
- ZAK is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- UniGene ID
- Hs.444451
Related Products
Product | Cat No. |
---|---|
Ad-h-ZAK | ADV-228028 |
AAV-h-ZAK-shRNA | shAAV-228028 |
Ad-h-ZAK-shRNA | shADV-228028 |
Control Products
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
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