human MELK Over-expression AAV

Name 
AAV-h-MELK
Cat No 
AAV-215293
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MELK.

AAV-215293
AAV-h-MELK

Ready-to-use AAV expressing Human MELK (maternal embryonic leucine zipper kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
hMELK; HPK38; maternal embryonic leucine zipper kinase; pEg3 kinase; protein kinase Eg3; protein kinase PK38; tyrosine-protein kinase MELK
Description (eCommerce)
Maternal embryonic leucine zipper kinase (MELK) phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may be involved in the inhibition of spliceosome assembly during mitosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q14680].
Gene ID
9833
Gene Name (eCommerce)
maternal embryonic leucine zipper kinase
Gene Name (Vector)
maternal embryonic leucine zipper kinase
Gene Symbol
MELK
HGNC ID
HGNC:16870
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1956
ORF Size (bp)
1956 bp
Protein Name (eCommerce)
Maternal embryonic leucine zipper kinase
RefSeq ID
NM_014791
RefSeq Synonyms
NM_014791, NM_001256693, NM_001256692, NM_001256691, NM_001256690, NM_001256689, NM_001256688, NM_001256687, NM_001256685, BC014039,
Research Areas
Apoptosis,Cell Cycle,Kinase/Phosphatase,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,neurobiology,signal_transduction
Species
human
Target Sentence
Maternal embryonic leucine zipper kinase (MELK) phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may be involved in the inhibition of spliceosome assembly during mitosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q14680].
UniGene ID
Hs.184339
UniProt ID (eCommerce)
Q14680

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.