human RHO Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-221169
Availability:
Immediate
Name:
AAV-h-RHO
This is an AAV expressing Human RHO.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RHO
- Gene Name
- rhodopsin
- Gene ID
- 6010
- Gene Synonyms
- CSNBAD1; OPN2; RP4
- ORF Size
- 1044 bp
- RefSeq#
- BC111451
- Gene Description
- Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
- UniGene ID
- Hs.247565
- HGNC ID
- HGNC:10012
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