human RHO shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-221170
Availability:
5-8 weeks
Name:
Ad-h-RHO-shRNA
This is an Adenovirus expressing shRNA for silencing of Human RHO.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RHO
- Gene Name
- rhodopsin
- Gene ID
- 6010
- Gene Synonyms
- CSNBAD1; OPN2; RP4
- ORF Size
- 1047 bp
- RefSeq#
- NM_000539
- Gene Description
- Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
- UniGene ID
- Hs.247565
- HGNC ID
- HGNC:10012
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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