human PRLR Over-expression AAV

Cat. No: AAV-219892

Availability: 3-5 weeks

Name: AAV-h-PRLR

This is an AAV expressing Human PRLR.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PRLR
Gene Name: prolactin receptor
Gene ID: 5618
Gene Synonyms: HPRL; hPRLrI; MFAB
ORF Size: 1869 bp
RefSeq#: BC059392
Gene Description: PRLR encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
UniGene ID: Hs.368587
HGNC ID: HGNC:9446