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human PRLR shRNA silencing AAV

Name 
AAV-h-PRLR-shRNA
Cat No 
shAAV-219892
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PRLR.

shAAV-219892
AAV-h-PRLR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PRLR (prolactin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HPRL; hPRLrI; MFAB
Description (Vector)
PRLR encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Gene ID
5618
Gene Name (Vector)
prolactin receptor
Gene Symbol
PRLR
HGNC ID
HGNC:9446
ORF Size (aa)
1869
ORF Size (bp)
1869 bp
RefSeq ID
NM_000949
RefSeq Synonyms
NM_001204318, NM_001204317, NM_001204316, NM_001204315, NM_001204314, NM_000949, BC059392,
Species
human
UniGene ID
Hs.368587

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.