human KLK5 Over-expression AAV

Cat. No: AAV-213301

Availability: 3-5 weeks

Name: AAV-h-KLK5

This is an AAV expressing Human KLK5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KLK5
Gene Name: kallikrein related peptidase 5
Gene ID: 25818
Gene Synonyms: KLK-L2; KLKL2; SCTE
ORF Size: 882 bp
RefSeq#: BC008036
Gene Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
UniGene ID: Hs.50915
HGNC ID: HGNC:6366