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human KLK5 shRNA silencing AAV

Name 
AAV-h-KLK5-shRNA
Cat No 
shAAV-213301
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KLK5.

shAAV-213301
AAV-h-KLK5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KLK5 (kallikrein related peptidase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KLK-L2; KLKL2; SCTE
Description (Vector)
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
25818
Gene Name (Vector)
kallikrein related peptidase 5
Gene Symbol
KLK5
HGNC ID
HGNC:6366
ORF Size (aa)
882
ORF Size (bp)
882 bp
RefSeq ID
NM_012427
RefSeq Synonyms
NM_012427, NM_001077492, NM_001077491, BC008036,
Species
human
UniGene ID
Hs.50915

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.