human GDNF Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-209792
Availability:
Immediate
Name:
AAV-h-GDNF
This is an AAV expressing Human GDNF.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GDNF
- Gene Name
- glial cell derived neurotrophic factor
- Gene ID
- 2668
- Gene Synonyms
- ATF; ATF1; ATF2; HFB1-GDNF; HSCR3
- ORF Size
- 636 bp
- RefSeq#
- BC128109
- Gene Description
- GDNF encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease.
- UniGene ID
- Hs.248114
- HGNC ID
- HGNC:4232
Related Products
Product | Cat No. |
---|---|
AAV-m-GDNF | AAV-260022 |
Ad-h-GDNF | ADV-209792 |
Ad-m-GDNF | ADV-260022 |
AAV-h-GDNF-shRNA | shAAV-209792 |
AAV-m-GDNF-shRNA | shAAV-260022 |
Ad-h-GDNF-shRNA | shADV-209792 |
Ad-m-GDNF-shRNA | shADV-260022 |
Control Products
Vector Biolabs
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