human EIF2B1 Over-expression AAV

Name
AAV-h-EIF2B1

Cat No
AAV-207710

Availability
4-5 weeks

This is an AAV expressing Human EIF2B1.

AAV-207710

AAV-h-EIF2B1

Ready-to-use AAV expressing Human EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EIF2B; EIF2BA

Description (Vector)

EIF2B1 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

Gene ID

1967

Gene Name (Vector)

eukaryotic translation initiation factor 2B subunit alpha

Gene Symbol

EIF2B1

HGNC ID

HGNC:3257

ORF Size (aa)

918

ORF Size (bp)

918 bp

RefSeq ID

NM_001414

RefSeq Synonyms

NM_001414, BC104189, BC104188, BC103763,

Species

human

UniGene ID

Hs.716475

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.