human EDA2R Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-207550
Availability:
3-5 weeks
Name:
AAV-h-EDA2R
This is an AAV expressing Human EDA2R.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- EDA2R
- Gene Name
- ectodysplasin A2 receptor
- Gene ID
- 60401
- Gene Synonyms
- EDA-A2R; EDAA2R; TNFRSF27; XEDAR
- ORF Size
- 894 bp
- RefSeq#
- BC034919
- Gene Description
- EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Alternatively spliced transcript variants have been found for this gene.
- UniGene ID
- Hs.302017
- HGNC ID
- HGNC:17756
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