human DOLK Over-expression AAV

Cat. No: AAV-207253

Availability: 3-5 weeks

Name: AAV-h-DOLK

This is an AAV expressing Human DOLK.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DOLK
Gene Name: dolichol kinase
Gene ID: 22845
Gene Synonyms: CDG1M; DK; DK1; SEC59; TMEM15
ORF Size: 1617 bp
RefSeq#: BC035556
Gene Description: DOLK catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.
UniGene ID: Hs.531563
HGNC ID: HGNC:23406