human BRMS1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-202273
Availability:
3-5 weeks
Name:
AAV-h-BRMS1
This is an AAV expressing Human BRMS1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- BRMS1
- Gene Name
- breast cancer metastasis suppressor 1
- Gene ID
- 25855
- ORF Size
- 741 bp
- RefSeq#
- BC009834
- Gene Description
- BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
- UniGene ID
- Hs.100426
- HGNC ID
- HGNC:17262
Related Products
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