mouse BRMS1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-277484
Availability:
3-5 weeks
Name:
AAV-m-BRMS1
This is an AAV expressing Mouse Brms1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Brms1
- Gene Name
- breast cancer metastasis-suppressor 1
- Gene ID
- 107392
- Gene Synonyms
- AV003220; AW554636
- ORF Size
- 426 bp
- RefSeq#
- BC003485
- Gene Description
- Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
- UniGene ID
- Mm.478009
Related Products
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