human ACD Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200181
Availability:
3-5 weeks
Name:
AAV-h-ACD
This is an AAV expressing Human ACD.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ACD
- Gene Name
- ACD, shelterin complex subunit and telomerase recruitment factor
- Gene ID
- 65057
- Gene Synonyms
- PIP1; PTOP; TINT1; TPP1
- ORF Size
- 1635 bp
- RefSeq#
- BC016904
- Gene Description
- ACD encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
- UniGene ID
- Hs.78019
- HGNC ID
- HGNC:25070
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