human ASB7 Over-expression AAV

Name 
AAV-h-ASB7
Cat No 
AAV-201535
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ASB7.

AAV-201535
AAV-h-ASB7

Ready-to-use AAV expressing Human ASB7 (ankyrin repeat and SOCS box containing 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
ASB7 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
Gene ID
140460
Gene Name (Vector)
ankyrin repeat and SOCS box containing 7
Gene Symbol
ASB7
HGNC ID
HGNC:17182
ORF Size (aa)
825
ORF Size (bp)
825 bp
RefSeq ID
NM_024708
RefSeq Synonyms
NM_198243, NM_024708, BC063581,
Species
human
UniGene ID
Hs.709044

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.