mouse PIN1 Over-expression AAV

Cat. No: AAV-268672

Availability: 3-5 weeks

Name: AAV-m-PIN1

This is an AAV expressing Mouse Pin1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pin1
Gene Name: protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
Gene ID: 23988
Gene Synonyms: 0610025L01Rik; D9Bwg1161e
ORF Size: 498 bp
RefSeq#: BC038254
Gene Description: Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.
UniGene ID: Mm.7906